Product features

  • Repairs 3-cm peripheral nerve defect

  • Biodegradable polymer

  • Good biocompatibility

  • Micro-structure designed for regeneration

  • Unique micro-design promotes nutrient exchange

Applications

  • Peripheral nerve injuries

  • Nerve graft and repair

Peripheral nerves play a key role in transmitting brain messages, controlling body sensation and muscles. After the damage, the sensory and motor functions of the human body are greatly affected. When the nerve gap is greater than 1 cm, other means to bridge the gap are required to connect both ends of normal nerves. Although the autograft is widely used for nerve repair, it will cause nerve damage to the area where the nerve is taken. Allograft posts other challenges as well. Even with additional process and treatment, immune reactions may still occur. ShineIN nerve conduit uses a biodegradable polymer. It replaces traditional autologous nerve grafting, has good biocompatibility, does not cause immune reaction, and can be degraded through metabolization normally after connection of nerve. It eliminates the need of secondary surgery, while avoiding autologous nerve transplantation. The unique micro-structure design of the nerve conduit promotes the exchange of inflammatory substances and nutrients, and guides the regenerating of the peripheral nerve up to 3 cm. This breakthrough set a new standard and is the first choice for peripheral nerve repair.

Picture 1: Nerve conduit used on sciatic nerve

Picture 2: MRI images of the regenerated nerve

References: Biomaterials. 2011 May;32(15):3764-75.

© 2018 ShineIN Biotechnology Co., Ltd.